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Fig. 4 | Respiratory Research

Fig. 4

From: Curdione ameliorates bleomycin-induced pulmonary fibrosis by repressing TGF-β-induced fibroblast to myofibroblast differentiation

Fig. 4

Curdione attenuated fibrotic markers expression following BLM induced. a Western blot analysis of fibrotic markers fibronectin, collagen 1 and α-SMA. Left panel: a representative western blot result. Right panel: a bar graph showing the mean data of all mice analyzed in each group. b-d RT-PCR analysis of fibrotic markers fibronectin, collagen 1 and α-SMA. e Immunostaining of fibronectin, collagen 1 and α-SMA in the lung sections. Images were taken under original magnification × 200. Twelve mice were included in each study group. Experimental results were expressed as mean ± standard deviation. The data were analysed by one-way ANOVA. *P < 0.05; **P < 0.01; ***P < 0.001

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