Mean change from baseline to week 52 | |||
---|---|---|---|
≤ 5% decline in FVC | > 5 to ≤ 10% decline in FVC | > 10% decline in FVC | |
SGRQ total score | −0.18 (n = 477) | 4.84** (n = 194) | 13.10***, ‡ (n = 152) |
SGRQ symptom score | −2.39 (n = 492) | 7.46*** (n = 198) | 9.40*** (n = 155) |
SGRQ activity score | 0.78 (n = 486) | 5.75** (n = 196) | 15.58***, ‡ (n = 154) |
SGRQ impacts score | 0.28 (n = 482) | 4.02* (n = 198) | 13.15***, ‡ (n = 153) |
UCSD-SOBQ | 3.02 (n = 441) | 7.65** (n = 176) | 15.85***, † (n = 132) |
CASA-Q cough symptom scorea | 2.47 (n = 495) | −3.90** (n = 201) | −5.27*** (n = 155) |
CASA-Q cough impact scorea | 1.38 (n = 495) | −6.48*** (n = 200) | −8.59*** (n = 156) |
EQ-5D VASa | −0.69 (n = 490) | −4.78** (n = 197) | −10.83***, † (n = 151) |