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Table 3 Correlation of clinical variables and phagocytosis-associated receptor expression of alveolar macrophages (multiple linear regression analysis)

From: Decreased expression of a phagocytic receptor Siglec-1 on alveolar macrophages in chronic obstructive pulmonary disease

  

FcγRI

MSR-1

Siglec-1

MFI ratio

% positive

MFI

% positive

MFI

% positive

Smoking history (Pack-years)

Estimate

0.0116

−0.1288

0.0105

0.0514

−0.0193

−0.2747

P value

0.7078

0.6213

0.2396

0.8057

0.2488

0.2935

FEV1 (% pred)

Estimate

0.0192

0.1153

0.0297

0.3519

−0.0057

−0.1107

P value

0.7158

0.7946

0.0548

0.3265

0.8397

0.8016

Low attenuation area scores

Estimate

−0.4466

−3.8890

−0.0002

−2.6940

−0.2661

−5.0410

P value

0.0731

0.0637

0.9982

0.1070

0.0463

0.0180

  1. Estimate represents parameter estimate
  2. Bold denotes values P < 0.05
  3. FEV1, forced expiratory volume in one second. MFI, mean fluorescence intensity
  4. MFI ratio indicates the ratio of receptor MFI to the corresponding FMO control MFI
  5. % positive indicates the percentage of a receptor-positive alveolar macrophages to total alveolar macrophages