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Table 2 Correlation of clinical variables and phagocytosis-associated receptor expression on alveolar macrophages (univariable analysis)

From: Decreased expression of a phagocytic receptor Siglec-1 on alveolar macrophages in chronic obstructive pulmonary disease

  

FcγRI

MSR-1

Siglec-1

MFI ratio

% positive

MFI

% positive

MFI

% positive

Age

rs

0.2735

0.1550

0.1842

0.1776

0.3462

0.3061

P value

0.1365

0.4051

0.3213

0.3392

0.0564

0.0940

Gender

rs

−0.2666

−0.3258

− 0.1852

− 0.2889

−0.3184

−0.3184

P value

0.0737

0.3185

0.1149

0.0809

0.0809

0.0737

Smoking history (Pack-years)

rs

−0.3670

− 0.3645

− 0.3568

− 0.3817

− 0.5333

− 0.4753

P value

0.0423

0.0438

0.0488

0.0341

0.0020

0.0069

FEV1 (% pred)

rs

0.4140

0.3533

0.5115

0.4459

0.4656

0.3958

P value

0.0206

0.0512

0.0033

0.0119

0.0083

0.0275

Low attenuation area scores

rs

−0.5358

−0.5577

−0.4564

−0.4945

−0.6778

−0.6440

P value

0.0019

0.0011

0.0099

0.0047

< 0.0001

< 0.0001

  1. Bold denotes values P < 0.05
  2. rs, Spearman rank correlation coefficient. FEV1, forced expiratory volume in 1 second. MFI, mean fluorescence intensity
  3. MFI ratio indicates the ratio of receptor MFI to the corresponding FMO control MFI
  4. % positive indicates the percentage of a receptor-positive alveolar macrophages to total alveolar macrophages
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Respiratory Research

ISSN: 1465-993X

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