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Table 3 Univariate and multivariate Cox proportional hazard regression analysis for development of tuberculosis

From: The impact on incident tuberculosis by kidney function impairment status: analysis of severity relationship

VariablesHR95% CIP-valueAdjusted HR95% CIP-value
Age, years (ref: ≤ 40)
 40–551.5811.2272.0370.00041.3921.0791.7970.0109
 55–652.5211.9753.218< 0.00012.0401.5922.614< 0.0001
 > 656.2405.0187.758< 0.00014.4393.5305.583< 0.0001
Male (ref: female)2.4602.1592.802< 0.00012.2581.9772.578< 0.0001
Kidney function
 CKD stage1 & 211
 CKD stage 3a2.3741.9582.879< 0.00011.2150.9951.4840.0563
 CKD stage 3b3.2322.5054.172< 0.00011.5381.1822.0020.0014
 CKD stage 44.2633.0655.930< 0.00012.0651.4732.894< 0.0001
 CKD stage 54.7923.1357.325< 0.00012.8771.8724.421< 0.0001
 Long-term dialysis2.4621.3194.5950.00462.0411.0923.8150.0254
 Kidney transplant20.3115.09081.050< 0.000115.2693.80661.2520.0001
COPD4.2713.1475.797< 0.00011.5811.1492.1740.0049
Asthma1.5741.0002.4790.0501    
Bronchiectasis4.6172.7267.822< 0.00012.9591.7175.098< 0.0001
Pneumoconiosis31.00416.08359.768< 0.000110.1495.19119.845< 0.0001
IPF3.2211.2078.5980.01951.4230.5223.8820.4903
GERD1.2870.9631.7200.0876    
Obesity0.1680.0241.1930.0745    
Cancer2.4092.0902.776< 0.00012.0061.7352.319< 0.0001
Cirrhosis2.1601.4413.2370.00021.2750.8471.9200.2440
Congestive heart failure3.1242.2684.302< 0.00011.7491.2622.4260.0008
Stroke1.3370.7892.2650.2806    
Diabetes mellitus1.9291.6472.259< 0.00011.2211.0371.4380.0166
SLE3.3112.0225.423< 0.00016.3233.80810.500< 0.0001
RA2.0871.2083.6060.00842.3051.3184.0340.0034
Dermatomyositis2.2130.31215.6810.4267    
Transplant, othersa2.1070.7905.6220.1364    
  1. Abbreviation: BMI Body mass index, CKD Chronic kidney disease, COPD Chronic obstructive pulmonary disease, eGFR Estimated glomerular filtration rate, GERD Gastroesophageal reflux disease, IPF Idiopathic pulmonary fibrosis, RA Rheumatoid arthritis, SLE Systemic lupus erythematosus
  2. aOther than kidney transplant
  3. The p value data in multivariate analysis are bold if < 0.05