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Table 1 Demographics of study population according to kidney function

From: The impact on incident tuberculosis by kidney function impairment status: analysis of severity relationship

VariablesCKDLong term dialysis (n = 1579)Kidney transplant (n = 38)P-value
nil or stage 1 (n = 129,421)2 (n = 128,248)3a (n = 17,228)3b (n = 7116)4 (n = 3449)5 (n = 2500)
Age (years)43.8 ± 15.255.5 ± 15.769.5 ± 12.471.6 ± 12.870.1 ± 14.262.7 ± 15.156.9 ± 14.454.8 ± 11.7< 0.0001
Age group< 0.0001
 ≤ 4057,461 (44.4)23,076 (18.0)409 (2.4)151 (2.1)141 (4.1)226 (9.0)204 (12.9)5 (13.2) 
 40–5538,907 (30.1)35,828 (27.9)1744 (10.1)613 (8.6)380 (11.0)514 (20.6)499 (31.6)12 (31.6) 
 55–6521,780 (16.8)31,925 (24.9)3430 (19.9)1175 (16.5)537 (15.6)586 (23.4)404 (25.6)14 (36.8) 
 > 6511,273 (8.7)37,419 (29.2)11,645 (67.6)5177 (72.8)2391 (69.3)1174 (47.0)472 (29.9)7 (18.4) 
Male gender51,354 (39.7)63,394 (49.4)8942 (51.9)3582 (50.3)1738 (50.4)1304 (52.2)804 (50.9)27 (71.1)< 0.0001
Serum Creatinine0.7 ± 0.10.9 ± 0.21.2 ± 0.21.7 ± 0.32.6 ± 0.66.8 ± 3.07.2 ± 3.22.6 ± 2.2<0.0001
eGFR108.2 ± 18.277.6 ± 8.053.8 ± 4.238.5 ± 4.323.3 ± 4.39.0 ± 3.311.4 ± 12.947.9 ± 31.9< 0.0001
COPD767 (0.6)1512 (1.2)491 (2.9)231 (3.3)92 (2.7)44 (1.8)10 (0.6)1 (2.6)< 0.0001
Asthma1320 (1.0)1566 (1.2)285 (1.7)117 (1.6)35 (1.0)20 (0.8)11 (0.7)0 (0.0)< 0.0001
Bronchiectasis389 (0.3)415 (0.3)53 (0.3)24 (0.3)12 (0.4)5 (0.2)0 (0.0)0 (0.0)0.3808
Pneumoconiosis34 (0.0)48 (0.0)13 (0.1)6 (0.1)1 (0.0)0 (0.0)3 (0.2)0 (0.0)NA
IPF182 (0.1)178 (0.1)32 (0.2)10 (0.1)9 (0.3)6 (0.2)1 (0.1)0 (0.0)NA
GERD4119 (3.2)5036 (3.9)630 (3.7)228 (3.2)101 (2.9)79 (3.2)47 (3.0)0 (0.0)< 0.0001
Obesity891 (0.7)685 (0.5)40 (0.2)13 (0.2)14 (0.4)7 (0.3)1 (0.1)0 (0.0)< 0.0001
Cancer14,895 (11.5)16,417 (12.8)2964 (17.2)1382 (19.4)645 (18.7)270 (10.8)197 (12.5)5 (13.2)< 0.0001
Cirrhosis1314 (1.0)1509 (1.2)400 (2.3)236 (3.3)132 (3.8)46 (1.8)37 (2.3)1 (2.6)< 0.0001
CHF662 (0.5)1543 (1.2)709 (4.1)501 (7.0)348 (10.1)231 (9.2)96 (6.1)1 (2.6)< 0.0001
Stroke763 (0.6)1381 (1.1)429 (2.5)221 (3.1)122 (3.5)55 (2.2)16 (1.0)1 (2.6)< 0.0001
Diabetes mellitus8179 (6.3)12,865 (10.0)3771 (21.9)2217 (31.2)1274 (36.9)961 (38.4)301 (19.1)8 (21.1)< 0.0001
SLE738 (0.6)409 (0.3)58 (0.3)29 (0.4)27 (0.8)31 (1.2)23 (1.5)0 (0.0)< 0.0001
RA802 (0.6)674 (0.5)94 (0.6)41 (0.6)22 (0.6)15 (0.6)8 (0.5)0 (0.0)0.1435
Polymyositis70 (0.1)28 (0.0)3 (0.0)2 (0.0)2 (0.1)1 (0.0)0 (0.0)0 (0.0)NA
Dermatomyositis73 (0.1)47 (0.0)1 (0.0)1 (0.0)2 (0.1)0 (0.0)0 (0.0)0 (0.0)NA
Transplant, others130 (0.1)204 (0.2)86 (0.5)41 (0.6)17 (0.5)6 (0.2)6 (0.4)2 (5.3)< 0.0001
  1. Abbreviation: BMI Body mass index, CHF Congestive heart failure, CKD Chronic kidney disease, COPD Chronic obstructive pulmonary disease, eGFR Estimated glomerular filtration rate, GERD Gastroesophageal reflux disease, IPF Idiopathic pulmonary fibrosis, RA Rheumatoid arthritis, SLE Systemic lupus erythematosus
  2. The number means mean ± standard deviation and number (%)
  3. Chi-square tests for categorical variables; ANOVA for continuous variables