Table 1 Demographics of study population according to kidney function
Variables | CKD | Long term dialysis (n = 1579) | Kidney transplant (n = 38) | P-value | |||||
|---|---|---|---|---|---|---|---|---|---|
nil or stage 1 (n = 129,421) | 2 (n = 128,248) | 3a (n = 17,228) | 3b (n = 7116) | 4 (n = 3449) | 5 (n = 2500) | ||||
Age (years) | 43.8 ± 15.2 | 55.5 ± 15.7 | 69.5 ± 12.4 | 71.6 ± 12.8 | 70.1 ± 14.2 | 62.7 ± 15.1 | 56.9 ± 14.4 | 54.8 ± 11.7 | < 0.0001 |
Age group | < 0.0001 | ||||||||
≤ 40 | 57,461 (44.4) | 23,076 (18.0) | 409 (2.4) | 151 (2.1) | 141 (4.1) | 226 (9.0) | 204 (12.9) | 5 (13.2) | |
40–55 | 38,907 (30.1) | 35,828 (27.9) | 1744 (10.1) | 613 (8.6) | 380 (11.0) | 514 (20.6) | 499 (31.6) | 12 (31.6) | |
55–65 | 21,780 (16.8) | 31,925 (24.9) | 3430 (19.9) | 1175 (16.5) | 537 (15.6) | 586 (23.4) | 404 (25.6) | 14 (36.8) | |
> 65 | 11,273 (8.7) | 37,419 (29.2) | 11,645 (67.6) | 5177 (72.8) | 2391 (69.3) | 1174 (47.0) | 472 (29.9) | 7 (18.4) | |
Male gender | 51,354 (39.7) | 63,394 (49.4) | 8942 (51.9) | 3582 (50.3) | 1738 (50.4) | 1304 (52.2) | 804 (50.9) | 27 (71.1) | < 0.0001 |
Serum Creatinine | 0.7 ± 0.1 | 0.9 ± 0.2 | 1.2 ± 0.2 | 1.7 ± 0.3 | 2.6 ± 0.6 | 6.8 ± 3.0 | 7.2 ± 3.2 | 2.6 ± 2.2 | <0.0001 |
eGFR | 108.2 ± 18.2 | 77.6 ± 8.0 | 53.8 ± 4.2 | 38.5 ± 4.3 | 23.3 ± 4.3 | 9.0 ± 3.3 | 11.4 ± 12.9 | 47.9 ± 31.9 | < 0.0001 |
COPD | 767 (0.6) | 1512 (1.2) | 491 (2.9) | 231 (3.3) | 92 (2.7) | 44 (1.8) | 10 (0.6) | 1 (2.6) | < 0.0001 |
Asthma | 1320 (1.0) | 1566 (1.2) | 285 (1.7) | 117 (1.6) | 35 (1.0) | 20 (0.8) | 11 (0.7) | 0 (0.0) | < 0.0001 |
Bronchiectasis | 389 (0.3) | 415 (0.3) | 53 (0.3) | 24 (0.3) | 12 (0.4) | 5 (0.2) | 0 (0.0) | 0 (0.0) | 0.3808 |
Pneumoconiosis | 34 (0.0) | 48 (0.0) | 13 (0.1) | 6 (0.1) | 1 (0.0) | 0 (0.0) | 3 (0.2) | 0 (0.0) | NA |
IPF | 182 (0.1) | 178 (0.1) | 32 (0.2) | 10 (0.1) | 9 (0.3) | 6 (0.2) | 1 (0.1) | 0 (0.0) | NA |
GERD | 4119 (3.2) | 5036 (3.9) | 630 (3.7) | 228 (3.2) | 101 (2.9) | 79 (3.2) | 47 (3.0) | 0 (0.0) | < 0.0001 |
Obesity | 891 (0.7) | 685 (0.5) | 40 (0.2) | 13 (0.2) | 14 (0.4) | 7 (0.3) | 1 (0.1) | 0 (0.0) | < 0.0001 |
Cancer | 14,895 (11.5) | 16,417 (12.8) | 2964 (17.2) | 1382 (19.4) | 645 (18.7) | 270 (10.8) | 197 (12.5) | 5 (13.2) | < 0.0001 |
Cirrhosis | 1314 (1.0) | 1509 (1.2) | 400 (2.3) | 236 (3.3) | 132 (3.8) | 46 (1.8) | 37 (2.3) | 1 (2.6) | < 0.0001 |
CHF | 662 (0.5) | 1543 (1.2) | 709 (4.1) | 501 (7.0) | 348 (10.1) | 231 (9.2) | 96 (6.1) | 1 (2.6) | < 0.0001 |
Stroke | 763 (0.6) | 1381 (1.1) | 429 (2.5) | 221 (3.1) | 122 (3.5) | 55 (2.2) | 16 (1.0) | 1 (2.6) | < 0.0001 |
Diabetes mellitus | 8179 (6.3) | 12,865 (10.0) | 3771 (21.9) | 2217 (31.2) | 1274 (36.9) | 961 (38.4) | 301 (19.1) | 8 (21.1) | < 0.0001 |
SLE | 738 (0.6) | 409 (0.3) | 58 (0.3) | 29 (0.4) | 27 (0.8) | 31 (1.2) | 23 (1.5) | 0 (0.0) | < 0.0001 |
RA | 802 (0.6) | 674 (0.5) | 94 (0.6) | 41 (0.6) | 22 (0.6) | 15 (0.6) | 8 (0.5) | 0 (0.0) | 0.1435 |
Polymyositis | 70 (0.1) | 28 (0.0) | 3 (0.0) | 2 (0.0) | 2 (0.1) | 1 (0.0) | 0 (0.0) | 0 (0.0) | NA |
Dermatomyositis | 73 (0.1) | 47 (0.0) | 1 (0.0) | 1 (0.0) | 2 (0.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) | NA |
Transplant, others | 130 (0.1) | 204 (0.2) | 86 (0.5) | 41 (0.6) | 17 (0.5) | 6 (0.2) | 6 (0.4) | 2 (5.3) | < 0.0001 |