Table 1 Baseline characteristics of the study cohort (n = 606)
From: The impact of COPD on polyneuropathy: results from the German COPD cohort COSYCONET
Parameter | all | Negative Neuroscore | Positive Neuroscore | p-value |
|---|---|---|---|---|
continuous | 25/50/75 percentile | 25/50/75 percentile | 25/50/75 percentile | |
Age (y) | 61.0/67.0/73.0 | 61.0/67.0/72.0 | 61.0/68.0/73.0 | 0.311 |
BMI (kg/m2) | 23.1/25.8/29.0 | 22.9/25.6/28.7 | 23.2/26.0/29.3 | 0.271 |
Packyears | 20.0/40.0/61.5 | 16.1/37.5/57.5 | 23.4/42.3/66.1 | 0.019 |
FEV1% predicted | 40.4/54.3/68.5 | 40.4/54.6/69.3 | 40.7/54.0/68.1 | 0.845 |
FVC % predicted | 68.3/82.4/96.6 | 67.6/82.3/96.1 | 68.5/82.6/97.7 | 0.553 |
RV/TLC (L) | 0.46/0.54/0.62 | 0.46/0.54/0.61 | 0.47/0.53/0.62 | 0.883 |
TLCO % predicted | 43.4/56.6/73.6 | 43.3/56.7/75.7 | 43.4/56.4/71.6 | 0.614 |
ABI | 1.12/1.21/1.29 | 1.13/1.22/1.30 | 1.11/1.20/1.28 | 0.098 |
SaO2 (%) | 92.9/94.4/95.7 | 93.0/94.3/95.7 | 92.8/94.5/95.7 | 0.985 |
paO2 (mmHg) | 61.6/67.1/73.4 | 62.0/67.5/73.0 | 60.9/67.0/73.5 | 0.704 |
paCO2 (mmHg) | 34.7/37.0/39.6 | 34.6/36.9/39.0 | 34.8/37.2/40.0 | 0.109 |
pH | 7.41/7.43/7.44 | 7.41/7.43/7.45 | 7.41/7.43/7.44 | 0.668 |
BE (mmol/l) | −0.7/0.6/1.9 | −0.9/0.5/1.8 | −0.5/0.9/2.0 | 0.040 |
CaO2 (ml/100 ml) | 17.6/18.6/19.7 | 17.8/18.8/20.0 | 17.5/18.4/19.4 | 0.002 |
CRP (mg/dl) | 2.0/4.0/8.0 | 1.8/3.6/6.7 | 2.0/4.0/9.6 | 0.136 |
eGFR (ml/min) | 68.8/82.5/93.3 | 69.6/83.3/93.2 | 67.6/80.8/93.5 | 0.254 |
Tuning fork result BTBJ | 5.4/6.5/7.5 | 5.5/7.0/7.5 | 5.0/6.0/7.5 | 0.003 |
Tuning fork result EJ | 5.0/6.5/7.5 | 5.0/6.5/7.5 | 4.5/6.0/7.5 | 0.720 |
Monofilament result | 9.5/10.0/10.0 | 10.0/10.0/10.0 | 9.0/10.0/10.0 | 0.310 |
6-MWD(m) | 378/451/520 | 395/465/530 | 365/439/504 | 0.010 |
TUG (s) | 5.40/5.42/7.60 | 5.1/6.4/7.4 | 5.7/6.5/7.9 | 0.122 |
categorical | ||||
Gender (m/f) | 362/244 | 201/114 | 161/130 | 0.020 |
Exacerbation risk (CD/AB) | 181/425 | 94/221 | 87/204 | 0.529 |