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Table 2 Hierarchical stepwise linear regression considering FEV1% variation as dependent variable and Nrf2, HO-1 and GCLC mRNA, plasma GSH, plasma 8-iso % variation and baseline smoking history (pack-year) as independent variables in COPD group (n.33)

From: Oxidative stress and Nrf2 expression in peripheral blood mononuclear cells derived from COPD patients: an observational longitudinal study

Independent variable Standardized Beta coefficients P value R2 Predicted R2
FEV1% variation
 Nr2 mRNA (% variation) 0.405 0.001   
 HO-1 mRNA (% variation) 0.364 0.006   
 GCLC mRNA (% variation) 0.322 0.015   
 plasma 8-iso (% variation) 0.096 0.315   
 plasma GSH (% variation) 0.074 0.403   
 pack-year 0.059 0.477   
    0.895 0.881