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Table 2 Comparison of clinical characteristics between quadrants at baseline

From: “Can do, don’t do” are not the lazy ones: a longitudinal study on physical functioning in patients with COPD

 

“Can’t do, don’t do” N = 85

“Can do, don’t do” N = 81

“Can’t do, do do” N = 13

“Can do, do do” N = 104

Overall p-value

Age, y

64 (60/69)

64 (58/67)

56 (53/60)*

64 (58/68)

0.007

Male, N (%)

63 (74)

51 (63)

7 (54)

63 (61)

0.180

BMI, kg/m2

24.9 (21.1/28.1)

26.6 (22.8/29.4)

24.0 (22.6/25.8)

26.7 (22.6/29.2)

0.110

Waist/Hip ratio

0.98 (0.90/1.05)

0.98 (0.93/1.02)

0.93 (0.90/1.02)

0.96 (0.89/1.01)

0.250

Smoker, N (%)

11 (13)

25 (31)*

2 (15)

29 (28)*

0.026

mMRC score

3 (2/3)

1 (1/2)*

2 (1/3)

1 (1/2)* †‡

< 0.001

CAT score

18 (14/23)

14 (10/18)*

19 (13/22)

13 (8/19)*

< 0.001

Anxiety score

5 (3/8)

3 (2/6)

7 (5/9)

4.5 (2.0/8.0)

0.080

Depression score

6 (4/8)

4 (2/6)*

5 (2/8)

3.5 (1.0/6.0)*

< 0.001

GOLD, N (%)

    

< 0.001

 I

2 (2)

6 (7)

0 (0)

17 (16)*

 

 II

11 (13)

27 (33)*

6 (46)*

48 (46)*

 

 III

35 (41)

36 (44)

3 (23)

29 (28)

 

 IV

37 (44)

12 (15)*

4 (31)

10 (10)*

 

COPD Risk Group, N (%)

    

< 0.001

 A

4 (5)

16 (20)*

1 (8)

27 (26)*

 

 B

68 (80)

54 (67)

10 (77)

60 (58)*

 

 C

1 (1)

0 (0)

0 (0)

8 (8)*

 

 D

12 (14)

11 (14)

2 (15)

9 (9)

 

FEV1, % pred.

31 (25/43)

45 (34/65)*

41 (29/56)

58 (40.5/75.0)*

< 0.001

RV/TLC, %

63 (57/68)

55 (45/65)*

55 (46/62)

52 (43/59)*

< 0.001

TLco, % pred.

36 (28/45)

47 (36/64)*

43 (34/48)

63 (46/78)*†‡

< 0.001

PaO2, kPa

8.6 (7.6/9.5)

9.0 (8.4/10.1)

9.3 (8.5/9.6)

9.6 (8.8/10.5)*

< 0.001

PaCO2, kPa

5.2 (4.7/5.7)

5.0 (4.5/5.3)*

5.0 (4.7/5.2)

4.9 (4.6/5.4)

0.047

SaO2, %

93.7 (91.2/95.3)

94.8 (93.3/96.0)

94.8 (94.5/96.0)

95.2 (93.7/96.5)*

0.007

Number of comorbidities, N

3 (2/5)

3 (2/5)

2 (1/2)*

2 (1.0/3.5)*

< 0.001

Exacerbations in the previous year, N

1 (0/2)

0 (0/1)

1 (0/2)

0 (0/1)*

< 0.001

Severe exacerbations in the previous year, N

0 (0/1)

0 (0/0)*

0 (0/0)

0 (0/0)*

0.006

Frequent exacerbator, N (%)

28 (33)

20 (25)

6 (46)

14 (14)*

0.004

Survival time, days (N = 214)

1550 (836/2268)a

2115 (1599/2394)b

2390 (1799/3019)c

2279 (1944/2839)d*

< 0.001

Retired person, N (%)

64 (76)

56 (70)

7 (54)

64 (62)

0.130

6MWD, m

300 (252/349)

450 (390/510)*

360 (300/375)

495 (444/562)*

< 0.001

6MWD, % pred.

57 (47/65)

87 (77/95)*

61 (56/65)

96 (95/107)*

< 0.001

SpO2 after 6MWT, %

87 (81/92)

90 (85/93)*

91 (87/95)

92 (87/95)*

< 0.001

Steps per day, N

2388 (1329/3357)

3284 (2113/3864)

6590 (6007/9258)*

7553 (5876/9819)*

< 0.001

  1. Values are median (25%/75% quartiles) unless otherwise stated. * p < 0.05 vs “can’t do, don’t do”; p < 0.05 vs “can do, don’t do”; p < 0.005 vs “can’t do, do do”. aN = 69; bN = 62; cN = 8;dN = 75. BMI body mass index, mMRC modified medical research council, CAT COPD assessment test, FEV1 forced expiratory volume in one second, RV/TLC residual volume to total lung capacity ratio, TLco diffusing capacity of the lung for carbon monoxide, PaO2 partial pressure of oxygen, PaCO2 partial pressure of carbon dioxide, SaO2 oxygen saturation, 6MWD 6-min walking distance