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Table 1 Pre-transplant characteristics of lung transplant patients and donors

From: Extracorporeal membrane oxygenation as a bridge to lung transplantation: analysis of Korean organ transplantation registry (KOTRY) data

 

Overall (N = 112)

Bridge-ECMO group (n = 27)

Non-bridge-ECMO group (n = 85)

p

Demographics

 Age, y

58.0 [52.5–62.0]

58.0 [53.0–62.0]

58.0 [52.0–62.0]

0.859

 Sex (Male)

71 (63.4%)

21 (77.8%)

50 (58.8%)

0.121

 BMI (kg/m2)

21.2 [19.0–23.5]

21.4 [18.7–23.4]

21.2 [19.1–23.5]

0.999

Primary diagnosis, n (%)

   

0.187

 Idiopathic pulmonary fibrosis

60 (53.6%)

13 (48.1%)

47 (55.3%)

 

 Other fibrosis/Emphysema

7 (6.2%)

1 (3.7%)

6 (7.1%)

 

 CTD related interstitial lung disease

20 (17.9%)

5 (18.5%)

15 (17.6%)

 

 Bronchiolitis obliterans after HSCT

10 (8.9%)

2 (7.4%)

8 (9.4%)

 

 Acute respiratory distress syndrome

8 (7.1%)

5 (18.5%)

3 (3.5%)

 

 Othersa

7 (6.2%)

1 (3.7%)

6 (7.1%)

 

Pre-transplantation status

 PaO2/FiO2 ratio

224.0 [125.0–281.0]

110.0 [82.5–251.0]

229.0 [181.0–288.0]

0.008

 LVEF, %

62.0 [59.0–67.0]

61.0 [56.0–65.0]

63.0 [59.0–68.0]

0.298

 RVSP, mmHg

50.0 [41.0–66.0]

61.0 [47.0–88.0]

48.5 [40.5–64.5]

0.141

 Preoperative MV, n (%)

39 (34.8%)

27 (100.0%)

12 (14.1%)

<  0.001

 Wait-list duration (day)

69.5 [18.5–127.5]

27.0 [10.5–40.5]

87.0 [35.0–145.0]

<  0.001

Donor demographics

 Sex (Male)

66 (58.9%)

16 (59.3%)

50 (58.8%)

1.000

 Age, y

41.5 [32.0–49.0]

38.0 [33.5–47.0]

43.0 [31.0–50.0]

0.464

 BMI (kg/m2)

22.1 [20.1–24.2]

20.9 [20.0–23.2]

22.7 [20.1–25.1]

0.122

Donor cause of brain death, n (%)

   

0.053

 Trauma

37 (33.0%)

12 (44.4%)

25 (29.4%)

 

 Underlying disease progression

27 (24.1%)

8 (29.6%)

19 (22.4%)

 

 Suicide

25 (22.3%)

7 (25.9%)

18 (21.2%)

 

Donor current smoker, n (%)

46 (41.1%)

7 (25.9%)

39 (45.9%)

0.043

  1. BMI body mass index, CTD connective tissue disease, HSCT hematopoietic stem cell transplantation, FEV1 forced expiratory volume in 1 s, PaO2 arterial oxygen tension, FiO2 fractional inspired oxygen, LVEF left ventricular ejection fraction, RVSP right ventricular systolic pressure, MV mechanical ventilation, ECMO extracorporeal membrane oxygenation
  2. aOthers include 3 bronchiectasis patients, 2 lymphangioleiomyomatoses patients, one Eisenmenger syndrome patient who received both heart and lung transplants, and one secondary pulmonary arterial hypertension patient