Cardiometabolic comorbidities in obstructive sleep apnea patients are related to disease severity, nocturnal hypoxemia, and decreased sleep quality

Table 6 Linear regression analysis for the influence of multiple cardiac-independent variables (CVCo) on quantitative dependent variables

		Model 1: CVCo			Model 2: CVCo + adjustement (age, BMI, smoking, sex, dyslipidemia)
	Dependent variables	R	R²	P value	R	R²	P value
Demographic data	NC	0.092	0.007	0.001	0.722	0.519	<0.0001
Demographic data	Alcool	0.095	0.007	0.005	0.263	0.065	<0.0001
Polysomnographic data	AHI	0.060	0.002	0.049	0.352	0.120	<0.0001
	AHI / REM	0.064	0.003	0.034	0.348	0.118	<0.0001
	AHI / NREM	0.054	0.002	NS	0.341	0.112	<0.0001
	SE (%)	0.064	0.003	0.047	0.268	0.067	<0.0001
	TST (min)	0.079	0.005	0.010	0.376	0.137	<0.0001
	N3 (%)	0.023	0.001	NS	0.074	0.001	NS
	REM (%)	0.130	0.016	<0.0001	0.215	0.042	<0.0001
	ARI	0.120	0.013	<0.0001	0.196	0.034	<0.0001
	Mean duration AH REM (sec)	0.092	0.007	0.001	0.200	0.036	<0.0001
	Mean duration AH NREM (sec)	0.021	0.001	NS	0.217	0.043	<0.0001
	PLM	0.027	< 0.0001	NS	0.142	0.018	<0.0001
	ODI (h)	0.009	0.001	NS	0.250	0.059	<0.0001
	Mean 02 saturation TST (%)	0.101	0.009	< 0.0001	0.176	0.027	<0.0001
	02 desaturation < 90% (min)	0.067	0.003	0.024	0.261	0.064	<0.0001
	Minimal 02 saturation (%)	0.092	0.007	0.001	0.283	0.076	<0.0001
	Mean HR (beats/min)	0.121	0.014	<0.0001	0.363	0.128	<0.0001

CVCo Cardiovascular Comorbidities, BMI Body mass index, NC Neck circumference, AHI Apnea-hypopnea index, AH Apnea-hypopnea, REM Rapid eye movement sleep, NREM Non-rapid eye movement sleep, SL Sleep latency, TST Total sleep time, SE Sleep efficiency, N3 Sleep stage 3, PLM Periodic leg movements index, ODI Oxygen desaturation index, ARI Arousal index, 0₂ Oxygen, HR Heart rhythm. All the results are expressed as Mean + SD. NS Not significant

ISSN: 1465-993X