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Fig. 6 | Respiratory Research

Fig. 6

From: ZDHXB-101 (3′,5-Diallyl-2, 4′-dihydroxy-[1,1′-biphen-yl]-3,5′-dicarbaldehyde) protects against airway remodeling and hyperresponsiveness via inhibiting both the activation of the mitogen-activated protein kinase and the signal transducer and activator of transcription-3 signaling pathways

Fig. 6

Effects of ZDHXB-101 on goblet cell hyperplasia and collagen deposition. a Lung sections were stained with PAS to assess goblet cell hyperplasia. PAS-positive and PAS-negative epithelial cells were counted, and the percentage of PAS-positive cells per bronchiole was calculated (histogram). b Lung sections were stained with Masson’s trichrome stains for the measurement of the subepithelial deposition of collagen and fibrosis. A Masson’s trichrome staining analysis of collagen deposition was conducted (histogram). The data represent means ± S.D. (n = 10), ***p < 0.001 vs. the control group. #p < 0.05 and ##p < 0.01 vs. the model group. Scale bar: 40 μm

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