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Fig. 4 | Respiratory Research

Fig. 4

From: ZDHXB-101 (3′,5-Diallyl-2, 4′-dihydroxy-[1,1′-biphen-yl]-3,5′-dicarbaldehyde) protects against airway remodeling and hyperresponsiveness via inhibiting both the activation of the mitogen-activated protein kinase and the signal transducer and activator of transcription-3 signaling pathways

Fig. 4

Effects of ZDHXB-101 on airway inflammation. a The total number of inflammatory cells in the BALF was counted, the (b) differential cells were determined in the BALF by Wright-Giemsa staining and cell classification was performed on a minimum of 200 cells to classify eosinophils, neutrophils, lymphocytes and macrophages 24 h after the final antigen challenge. c Lung sections were stained with H&E for the measurement of inflammatory cells infiltration in the peribronchiolar space. Inflammatory cell infiltration was graded based on the severity of inflammation (histogram). The data represent the means ± S.D. (n = 10). ***p < 0.001 vs. the control group. #p < 0.05 and ##p < 0.01 vs. the model group. Scale bar: 40 μm

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