Table 8 Top three items of GO and KEGG analysis. Annotation: GO, gene ontology; BP, biological process; CC, cellular component; MF, molecular function; KEGG, Kyoto Encyclopedia of Genes and Genomes
Category | ID | Term | Count | % | P value | Genes |
|---|---|---|---|---|---|---|
BP | GO:0001764 | neuron migration | 13 | 0.015581 | 3.06E-06 | PHOX2B, NDE1, SATB2, CDK5R1, CDK5R2, NAV1, SOX1, NTRK2, CELSR3, NEUROD4, DCX, FBXO45, PITX2 |
BP | GO:0051965 | positive regulation of synapse assembly | 8 | 0.009588 | 4.35E-04 | SLITRK1, SRPX2, NTRK2, IL1RAP, EFNA5, TPBG, EPHB1, EPHB2 |
BP | GO:0008284 | positive regulation of cell proliferation | 17 | 0.020375 | 6.96E-04 | CDC7, FGF5, HMX2, E2F3, RARG, PKHD1, SOX4, GREM1, EPHA1, GDNF, IL11, HDAC1, TFAP2B, POU3F2, EIF5A2, DPP4, DLG1 |
CC | GO:0043005 | neuron projection | 12 | 0.014382 | 2.91E-04 | TENM4, TENM1, KIF5A, STMN2, SLC6A2, OPRK1, BCL11B, KIF5C, STMN4, GABBR2, DCX, CALB1 |
CC | GO:0005887 | integral component of plasma membrane | 38 | 0.045544 | 7.23E-04 | GPR83, SLC5A3, SLC13A5, SLC20A2, SLC6A2, OPRK1, LRRC8D, GNRHR, CNGB3, SLC52A3, LGR4, EPHB1, EPHB2, EPCAM, ADRA2A, HCN3, HCN1, SLC12A7, GABRG2, CLCA2, RET, SLC6A17, MMP15, EPHA1, GRM1, SLC7A11, TIGIT, TENM4, EPHA7, SLC16A7, TMPRSS11D, TENM1, SLC6A8, SLC17A4, NTRK2, CLDN1, KCNH8, HAS3 |
CC | GO:0005667 | transcription factor complex | 12 | 0.014382 | 0.005459 | E2F3, SATB2, BARX2, RARG, HNF1A, TRPS1, SIX1, TP63, POU3F2, TBL1X, TP73, PITX2 |
MF | GO:0005248 | voltage-gated sodium channel activity | 5 | 0.005993 | 5.84E-04 | HCN1, SCN8A, SCN5A, HCN3, SCN4A |
MF | GO:0005249 | voltage-gated potassium channel activity | 7 | 0.00839 | 8.94E-04 | HCN1, KCNQ5, KCNH8, KCNA7, HCN3, CNGB3, KCNE4 |
MF | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | 15 | 0.017978 | 0.001203 | PHOX2B, FOXL2, SOX1, ONECUT2, SOX4, TP63, SIX2, HLTF, TP73, HOXC11, BCL11B, SIX1, TFAP2B, TFAP2A, POU3F2 |
KEGG | cfa05206 | MicroRNAs in cancer | 10 | 0.011985 | 0.005364 | E2F1, DNMT3A, E2F3, WNT3, MMP9, IGF2BP1, TP63, CDK6, MMP16, HMGA2 |
KEGG | cfa04514 | Cell adhesion molecules (CAMs) | 8 | 0.009588 | 0.039758 | TIGIT, SDC1, CLDN19, CLDN1, CNTNAP2, VCAN, NRXN1, CDH2 |
KEGG | cfa04550 | Signaling pathways regulating pluripotency of stem cells | 8 | 0.009588 | 0.04251 | DVL3, FZD10, WNT3, HNF1A, INHBE, JARID2, NEUROG1, JAK3 |