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Fig. 2 | Respiratory Research

Fig. 2

From: Downregulation of hsa-microRNA-204-5p and identification of its potential regulatory network in non-small cell lung cancer: RT-qPCR, bioinformatic- and meta-analyses

Fig. 2

Expression of miR-204-5p in non-small cell lung cancer (NSCLC) and subgroups derived from RT-qPCR and TCGA database. a Scatter plot for RT-qPCR indicated significantly lower miR-204-5p expression in NSCLC tissues (3.6760 ± 1.87670) than in the controls (4.6487 ± 2.46888) (P = 0.001). b Expression differences for miR-204-5p between lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) determined by RT-qPCR. The decrease was more obvious in LUAD (3.4663 ± 1.82397) than in LUSC (4.6870 ± 1.80638) (P = 0.006). c Expression level of miRNA-sequencing data from TCGA revealed significantly lower miR-204-5p expression in NSCLC tissues (1.8877 ± 2.18763) than in healthy control tissues (2.5944 ± 0.9404) (P = 0.000). d Expression comparison of miR-204-5p between LUAD (1.3331 ± 1.64315) and LUSC from TCGA (2.4922 ± 2.52336). The difference was consistent with the foregoing data of RT-qPCR. (P = 0.000)

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