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Table 4 Factors associated with a progressive cavity

From: Characteristic chest CT findings for progressive cavities in Mycobacterium avium complex pulmonary disease: a retrospective cohort study

 

Univariable analysis

OR (95% CI)

p value

Multivariable analysis

OR (95% CI)

p value

Female sex

0.77 (0.27–2.24)

0.636

  

Age, years

1.11 (1.04–1.17)

0.001

1.12 (1.03–1.20)

0.005

Body mass index, kg/m2a

0.85 (0.71–1.01)

0.064

  

Causative organismb

Mycobacterium avium

1

   

Mycobacterium intracellulare

1.72 (0.74–4.04)

0.211

  

Sputum-smear positivityc

2.32 (0.95–5.63)

0.064

  

Diabetes mellitus

11.80 (1.46–95.52)

0.021

7.80 (0.71–86.12)

0.094

Multidrug regimend

1.21 (0.47–3.12)

0.700

  

Chest CT findings at the initial cavity

 Cavity in the middle lobe or lingual

0.14 (0.03–0.68)

0.015

  

 Maximum inner diameter (mm)

1.12 (1.04–1.20)

0.002

1.11 (1.02–1.21)

0.012

 Shortest distance (mm)e

0.86 (0.76–0.96)

0.010

  

 Multiple cavities

2.81 (1.22–6.46)

0.015

1.08 (0.35–3.34)

0.892

Chest CT findings around the initial cavity

 Consolidation

16.40 (5.10–52.78)

< 0.001

16.15 (4.05–64.46)

< 0.001

 Atelectasis

4.56 (1.40–14.88)

< 0.001

  

 Pleural thickening

6.61 (2.67–16.35)

< 0.001

  

 Pleural indentation

0.42 (0.16–1.08)

0.072

  
  1. CI Confidence interval, CT Computed tomography, OR Odds ratio. a: Body mass index was checked for 75 patients. b: Mycobacterium avium complex species was checked for 96 patients. c: Sputum-smear positivity was checked for 83 patients. d: Multidrug regimen refers to CAM/AZM-containing regimen with two or more drugs for at least 1 year. e: The shortest distance is from the pleura to the outer wall of the cavity. p < 0.05 was considered significant