Table 1 Baseline characteristics of 97 patients with Mycobacterium avium complex pulmonary disease and cavitary lesions
Characteristic | Progressive cavity Group (n = 52) | Non-progressive cavity Group (n = 45) | P value |
|---|---|---|---|
Female | 42 (80.8) | 38 (84.4) | 0.790 |
Age, years | 68 (54–83) | 63 (51–78) | < 0.001 |
Body mass index, kg/m2a | 16.7 (12.3–24.6) | 18.3 (13.7–25.4) | 0.043 |
Underlying lung disease | |||
Pulmonary emphysema/bulla | 5 (9.6) | 3 (6.7) | 0.721 |
Old pulmonary tuberculosis | 8 (15.4) | 4 (8.9) | 0.373 |
Bronchiectasis | 50 (96.2) | 43 (95.6) | > 0.999 |
Interstitial pneumonia | 4 (7.7) | 2 (4.4) | 0.683 |
Comorbidity | |||
Chronic heart disease | 15 (28.8) | 14 (31.1) | 0.828 |
Diabetes mellitus | 11 (21.2) | 1 (2.2) | 0.005 |
Chronic liver disease | 3 (5.8) | 3 (6.7) | > 0.999 |
Collagen disease | 3 (5.8) | 2 (4.4) | > 0.999 |
Cerebrovascular disease | 3 (5.8) | 1 (2.2) | 0.621 |
Postgastrointestinal tract surgery | 3 (5.8) | 3 (6.7) | > 0.999 |
Steroid and/or immunosuppressive agent useb | 3 (5.9) | 2 (4.4) | > 0.999 |
MAC speciesc | |||
Mycobacterium avium | 28 (54.9) | 28 (62.2) | 0.536 |
Mycobacterium intracellulare | 21 (41.2) | 13 (28.9) | |
Both | 2 (3.9) | 4 (8.9) | |
Sputum-smear positived | 28 (66.7) | 19 (46.3) | 0.078 |
Treatment | |||
No treatment | 4 (7.7) | 8 (17.8) | |
Non-CAM/AZM-included regimen | 4 (7.7) | 3 (6.7) | |
Multidrug regimene | 41 (78.8) | 34 (75.6) | 0.809 |