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Fig. 3 | Respiratory Research

Fig. 3

From: Inhaled high molecular weight hyaluronan ameliorates respiratory failure in acute COPD exacerbation: a pilot study

Fig. 3

Improved lung function and serum markers of inflammation in HMW-HA treated patients. a HMW-HA-treated patients have lower peak pressures, as recorded by the NIV apparatus, throughout NIVVP. b paO2/FiO2 ratio improves significantly in HMW-HA patients. c paCO2 improves significantly in both groups. N = 17 per group. d Joint analysis of 4 serum inflammatory markers shows a significant improvement in HMW-HA treated patients, but not in placebo patients. e Among the 2 inflammatory markers (CRP and IL-6) that decreased with treatment in both groups in a, more robust improvement can be seen in HMW-HA patients compared to placebo-treated patients. N = 13 per group

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Respiratory Research

ISSN: 1465-993X

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