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Table 3 Patient distribution based on pulmonary function testing and associated 6-min walk test (6MWT) data

From: Idiopathic pulmonary fibrosis patients with severe physiologic impairment: characteristics and outcomes

 

All FVC%

FVC ≤ 50%

FVC ≤ 45%

FVC ≤ 40%

FVC > 50%

All DLco%

 n

242

147

92

45

95

 6MWD, m

304 ± 121

294 ± 123

275 ± 124

260 ± 120

318 ± 116

 \({\text{6MWT}}_{{{\text{O}}_{{2}} }}\)

61%

60%

65%

70%

61%

DLco > 35%

 n

24

24

14

5

0

 6MWD, m

366 ± 120

366 ± 120

356 ± 131

333 ± 138

 \({\text{6MWT}}_{{{\text{O}}_{{2}} }}\)

50%

50%

64%

60%

DLco ≤ 35%

 n

168

73

45

21

95

 6MWD, m

301 ± 119

277 ± 136

258 ± 123

264 ± 104

318 ± 116

 \({\text{6MWT}}_{{{\text{O}}_{{2}} }}\)

63%

67%

67%

76%

61%

DLco ≤ 30%

 n

151

57

34

15

95

 6MWD, m

298 ± 119

262 ± 117

246 ± 122

237 ± 102

318 ± 116

 \({\text{6MWT}}_{{{\text{O}}_{{2}} }}\)

64%

71%

67%

87%

61%

DLco ≤ 25%

 n

81

32

22

10

49

 6MWD, m

281 ± 123

253 ± 127

226 ± 119

219 ± 120

297 ± 119

 \({\text{6MWT}}_{{{\text{O}}_{{2}} }}\)

74%

74%

68%

80%

74%

DLco ≤ 20%

 n

31

16

12

7

15

 6MWD, m

246 ± 128

234 ± 114

237 ± 128

234 ± 125

257 ± 145

 \({\text{6MWT}}_{{{\text{O}}_{{2}} }}\)

77%

77%

70%

86%

77%

DLco not available

 n

50

50

33

19

0

 6MWD, m

281 ± 118

281 ± 118

261 ± 112

224 ± 81

 \({\text{6MWT}}_{{{\text{O}}_{{2}} }}\)

57%

57%

65%

79%

  1. PFT: pulmonary function test; FVC: forced vital capacity, % predicted; DLco: single breath diffusing capacity for carbon monoxide, % predicted; 6MWT; 6-min walk test; 6MWD: 6-min walk test distance, meters ± SD; \({\text{6MWT}}_{{{\text{O}}_{{2}} }}\): patients with need for supplemental oxygen during 6MWT