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Fig. 1 | Respiratory Research

Fig. 1

From: Resistin-like molecule β acts as a mitogenic factor in hypoxic pulmonary hypertension via the Ca2+-dependent PI3K/Akt/mTOR and PKC/MAPK signaling pathways

Fig. 1

Verification of the hypoxia-induced rat PAH model. The mean arterial wall thickness at different durations of hypoxia (H&E staining, optical microscope, 400 ×) (a). Morphometric analysis of rat pulmonary arterioles after exposure to normoxia (Control) or hypoxia for 7 days (H7), 14 days (H14) or 21 days (H21) (b). The mRVSP of rats exposed to normoxia or hypoxia for different durations (c). Time course of the RV/LV + S ratio in rats exposed to hypoxia (d). WT(%), ratio of vascular wall thickness to external diameter; LA(%), ratio of lumen area to total vascular area; WA(%), ratio of vascular wall area to total vascular area; n ≥ 6 in each group. *P < 0.05 versus the control group; #P < 0.05 versus group H7; △P < 0.05 versus group H14

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Respiratory Research

ISSN: 1465-993X

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