Skip to main content
Fig. 2 | Respiratory Research

Fig. 2

From: Can biomarkers of extracellular matrix remodelling and wound healing be used to identify high risk patients infected with SARS-CoV-2?: lessons learned from pulmonary fibrosis

Fig. 2

Schematic drawing of the basement membrane (in green) underlying the lung epithelium and the interstitial matrix (in red), supporting the tissue. After cellular damage the epithelium is compromised, clotting occurs which results in remodelling of the tissue. When overactivated, fibroblasts (blue) produce fibrillar collagen limiting oxygen diffusion. During these processes, small fragments of proteins related to these molecular events are released into the circulation, where they may be used as biomarkers

Back to article page
\