Table 3 AUC0–12 change from baseline
| Parameter | BDP/F/G | BDP/F | ||
|---|---|---|---|---|
| AUC0–12 mean change | p value | AUC0–12 mean change | p value | |
| FEV1 (mls) |
320 (257, 384) | < 0.0001 |
227 (163, 290) | < 0.0001 |
| FVC (mls) |
524 (420, 627) | < 0.0001 |
351 (248, 455) | < 0.0001 |
| FEF25–75% (L/sec) |
0.112 (0.080, 0.144) | < 0.0001 |
0.082 (0.050, 0.113) | < 0.0001 |
| sGaw (L/s/kPa/L) |
0.310 (0.259, 0.362) | < 0.0001 |
0.224 (0.172, 0.275) | < 0.0001 |
| Raw (kPa/L/s) |
− 0.298 (− 0.369, − 0.226) | < 0.0001 |
− 0.242 (− 0.313, − 0.170) | < 0.0001 |
| RV (mls) |
− 678 (− 847, − 509) | < 0.0001 |
− 558 (− 727, − 389) | < 0.0001 |
| IC (mls) |
328 (219, 438) | < 0.0001 |
289 (180, 399) | < 0.0001 |
| FRC (mls) |
− 468 (− 612, − 323) | < 0.0001 |
− 426 (− 571, − 282) | < 0.0001 |
| TLC (mls) |
− 136 (− 243, − 28) | 0.0144 |
− 132 (− 239, − 24) | 0.0174 |
| R5–R20 (kPa/L/s) |
− 0.165 (− 0.198, − 0.132) | < 0.0001 |
− 0.117 (− 0.150, − 0.084) | < 0.0001 |
| X5 (kPa/L/s) |
0.208 (0.169, 0.248) | < 0.0001 |
0.159 (0.120, 0.198) | < 0.0001 |
| ∆X5 (kPa/L/s) |
− 0.207 (− 0.262, − 0.152) | < 0.0001 |
− 0.140 (− 0.195, − 0.085) | < 0.0001 |
| Fres (1/s) |
− 8.235 (− 10.108, − 6.363) | < 0.0001 |
− 5.600 (− 7.472, − 3.727) | < 0.0001 |
| AX (kPa/L) |
− 2.991 (− 3.614, − 2.368) | < 0.0001 |
− 2.228 (− 2.851, − 1.604) | < 0.0001 |