Table 3 AUC0–12 change from baseline
Parameter | BDP/F/G | BDP/F | ||
|---|---|---|---|---|
AUC0–12 mean change | p value | AUC0–12 mean change | p value | |
FEV1 (mls) | 320 (257, 384) | < 0.0001 | 227 (163, 290) | < 0.0001 |
FVC (mls) | 524 (420, 627) | < 0.0001 | 351 (248, 455) | < 0.0001 |
FEF25–75% (L/sec) | 0.112 (0.080, 0.144) | < 0.0001 | 0.082 (0.050, 0.113) | < 0.0001 |
sGaw (L/s/kPa/L) | 0.310 (0.259, 0.362) | < 0.0001 | 0.224 (0.172, 0.275) | < 0.0001 |
Raw (kPa/L/s) | − 0.298 (− 0.369, − 0.226) | < 0.0001 | − 0.242 (− 0.313, − 0.170) | < 0.0001 |
RV (mls) | − 678 (− 847, − 509) | < 0.0001 | − 558 (− 727, − 389) | < 0.0001 |
IC (mls) | 328 (219, 438) | < 0.0001 | 289 (180, 399) | < 0.0001 |
FRC (mls) | − 468 (− 612, − 323) | < 0.0001 | − 426 (− 571, − 282) | < 0.0001 |
TLC (mls) | − 136 (− 243, − 28) | 0.0144 | − 132 (− 239, − 24) | 0.0174 |
R5–R20 (kPa/L/s) | − 0.165 (− 0.198, − 0.132) | < 0.0001 | − 0.117 (− 0.150, − 0.084) | < 0.0001 |
X5 (kPa/L/s) | 0.208 (0.169, 0.248) | < 0.0001 | 0.159 (0.120, 0.198) | < 0.0001 |
∆X5 (kPa/L/s) | − 0.207 (− 0.262, − 0.152) | < 0.0001 | − 0.140 (− 0.195, − 0.085) | < 0.0001 |
Fres (1/s) | − 8.235 (− 10.108, − 6.363) | < 0.0001 | − 5.600 (− 7.472, − 3.727) | < 0.0001 |
AX (kPa/L) | − 2.991 (− 3.614, − 2.368) | < 0.0001 | − 2.228 (− 2.851, − 1.604) | < 0.0001 |