Fig. 4From: Serum surfactant protein D as a predictive biomarker for the efficacy of pirfenidone in patients with idiopathic pulmonary fibrosis: a post-hoc analysis of the phase 3 trial in JapanEffect of pirfenidone on relative changes in serum concentrations of a SP-D, b SP-A and c KL-6 from baseline. Blue lines, pirfenidone; black lines, placebo. Mean ± SE. The comparison between the pirfenidone and placebo groups was performed using the Wilcoxon rank-sum test: *p < 0.05, **p < 0.01Back to article page