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Fig. 2 | Respiratory Research

Fig. 2

From: Serum surfactant protein D as a predictive biomarker for the efficacy of pirfenidone in patients with idiopathic pulmonary fibrosis: a post-hoc analysis of the phase 3 trial in Japan

Fig. 2

Relationship between serum concentrations of biomarkers at baseline and the efficacy of pirfenidone on changes in vital capacity from baseline. All patients were dichotomized by the median concentration of a SP-D, b SP-A and c KL-6 at baseline to the high and low biomarker subgroups. Blue lines, pirfenidone; black lines, placebo. Mean ± SE. Mean changes were calculated with the mixed model for repeated measurement (MMRM). *p < 0.05, **p < 0.01

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Respiratory Research

ISSN: 1465-993X

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