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Table 4 List of therapeutic candidates against COVID-19

From: SARS coronavirus 2: from genome to infectome

S. no

Drug name

Clinical trial

Trial

Treatment

References

1.

Pacritinib

Phase 3

NCT04404361

Kinase inhibitor

[170]

2.

Enoxaparin

Phase 3

NCT04401293

Antithrombotic

[171]

3.

Remdesivir + Baricitinib

Phase 3

NCT04401579

Antiviral

[172]

4.

Remdesivir

Phase 3

NCT04401579

Antiviral

[172]

5.

Hydroxychloroquine

Phase 3

NCT04410562

Antimalarial

[173]

6.

Favipiravir + Hydroxychloroquine

Phase 3

NCT04411433

Antiviral

[174, 175]

7.

ASC09 + Oseltamivir

Phase 3

NCT04261270

Antiviral

[176]

8.

ASC09 + Ritonavir

NA

NCT04261907

Antiviral

[176]

9.

Tocilizumab (IL-6)

Phase 3

NCT04412772

Monoclonal antibodies

[177]

10.

Anakinra

Phase 3

NCT04412291

Anti-inflammatory

[178]

11.

Ivermectin

Completed

NCT04422561

Antiparasitic

[179]

12.

Budesonide dry powder inhaler

Phase 2

NCT04416399

Corticosteroid

[180]

13.

LY3819253

Phase 3

NCT04427501

Corticosteroid

[181]

14.

Atazanavir and dexamethasone

Phase 3

NCT04452565

Corticosteroid and antiviral

[182]

15.

Colchicine

Phase 2

NCT04326790

Anti-inflammatory

[183]

16.

Corticosteroid

Phase 3

NCT04381936

Corticosteroid

[184]

17.

Azithromycin

Phase 3

NCT04381936

Antibacterial

[184]

18.

Convalescent plasma

Phase 3

NCT04425915

Convalescent plasma

[130]

19.

NA-831 and dexamethasone

Phase 3

NCT04452565

Corticosteroid

[182]

20.

Camostat Mesilate

Phase 2

NCT04470544

Protease inhibitor

[81]