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Fig. 7 | Respiratory Research

Fig. 7

From: RETRACTED ARTICLE: Targeting MALAT1 and miRNA-181a-5p for the intervention of acute lung injury/acute respiratory distress syndrome

Fig. 7

miR-181a-5p and anti-MALAT1 improved outcome in ALI/ARDS rats. LPS was injected i.p. to induced ALI/ARDS in rats 48 h after transfection of mimic miR-181a-5p or mimic NC and siR-MALAT1 or siR-NC. a, b H&E staining showing increased septal thickness, intra-alveolar transudates, and increased inflammatory cell infiltration in LPS group. c, d Increased Fas and TNF-α protein expression in lung tissue extracts determined by Western blotting. e H&E staining showed that both miR-181a-5p and siR-MALAT1 improved LPS-induced lung injury. f IQA scores were reduced by both miR-181a-5p and siR-MALAT1. *, **p < 0.05, 0.01.

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