Table 1 Change in Lung Function following BT
Baseline | 6 weeks post | 6 months post | p | |
|---|---|---|---|---|
Spirometry | ||||
FEV1 (l) preBD | 1.34 ± 0.65 | 1.42 ± 0.76 | 1.52 ± 0.76 | 0.024 |
FEV1 (% pred) | 45.6 ± 12.9 | 48.1 ± 14.9 | 52.3 ± 16.1 | 0.022 |
VC (l) preBD | 2.63 ± 0.93 | 2.68 ± 0.93 | 2.82 ± 0.97 | 0.017 |
VC (% pred) | 73.0 ± 13.5 | 76.6 ± 15.4 | 81.3 ± 18.9 | 0.029 |
Plethysmography | ||||
TLC (l) | 5.55 ± 1.33 | 5.66 ± 1.42 | 5.59 ± 1.32 | 0.692 |
TLC (% pred) | 100 ± 18 | 103 ± 26 | 102 ± 22 | 0.652 |
FRC (l) | 3.58 ± 1.07 | 3.42 ± 0.94 | 3.40 ± 1.05 | 0.218 |
FRC % | 121 ± 38 | 116 ± 29 | 115 ± 35 | 0.200 |
RV (l) | 2.87 ± 0.89 | 2.84 ± 1.08 | 2.71 ± 0.93 | 0.008 |
RV (% pred) | 145 ± 41 | 145 ± 55 | 139 ± 40 | 0.010 |
Raw (cmH2O s l−1) | 10.58 ± 6.56 | 9.09 ± 5.36 | 7.64 ± 3.74 | 0.020 |
Raw (% pred) | 346 ± 214 | 297 ± 175 | 248 ± 121 | 0.019 |
sRaw (cmH2O.s) | 40.8 ± 24.8 | 37.1 ± 25.9 | 30.5 ± 20.1 | 0.022 |
Nitrogen washout | ||||
LCI | 12.7 ± 3.3 | 12.2 ± 3.1 | 11.8 ± 2.4 | 0.049 |
Sacin (l−1) | 0.355 ± 0.164 | 0.327 ± 0.179 | 0.299 ± 0.165 | 0.380 |
Scond (l−1) | 0.063 ± 0.059 | 0.049 ± 0.062 | 0.069 ± 0.094 | 0.560 |