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Table 1 Baseline characteristics of the 3 groups, and comparison of their respective features

From: Could KL-6 levels in COVID-19 help to predict lung disease?

Baseline characteristics P values
  HSa (N = 70) COVID19 (N = 83) ILD (N = 31) HS vs COVID19 HS vs ILD ILD vs COVID19
Gender, M (%) 35 (50%) 52 (62.6%) 23(72%)  > 0.05  < 0.05  > 0.05
Age 58 (52–64) 72 (58–82) 69 (62–75)  < 0.001  > 0.05  < 0.01
Leukocytes (/ml) 6.21 (5.13–7.43) 6.3 (4.68–8.61) 8.77 (6.1–11.53)  > 0.05  < 0.01  < 0.01
Neutrophils (/mm3) 3.38 (2.81–4.22) 4.65 (3.32–7.21) 5.78 (4.31–8.19)  < 0.001  < 0.001  > 0.05
Lymphocytes (/mm3) 2.2 (1.71–2.49) 0.92 (0.65–1.23) 1.97 (0.87–2.2)  < 0.001  > 0.05  < 0.001
CRP (mg/L) 1.0 (0.5–2.4) 60 (27–146) 4.8 (2.1–9)  < 0.001  > 0.05  < 0.001
Fibrinogen (g/L) 2.88 (2.56–3.43) 5.24 (4.03–6.23) 3.43 (3.18–4.15)  < 0.001  > 0.05  < 0.01
KL-6 (U/mL) 254 (191–308) 405 (277–592) 897 (550–1885)  < 0.001  < 0.001  < 0.001
  1. Data are expressed in median (IQR, inter quartile range)
  2. Data are analyzed with Kruskall Wallis test and post Hoc: DunnTest and with Fisher’s test for the sex variable
  3. aHS (healthy subjects): Complete blood count: N = 62; CRP: N = 52; Fibrinogen: N = 46