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Table 1 Baseline characteristics of the 3 groups, and comparison of their respective features

From: Could KL-6 levels in COVID-19 help to predict lung disease?

Baseline characteristics

P values

 

HSa (N = 70)

COVID19 (N = 83)

ILD (N = 31)

HS vs COVID19

HS vs ILD

ILD vs COVID19

Gender, M (%)

35 (50%)

52 (62.6%)

23(72%)

 > 0.05

 < 0.05

 > 0.05

Age

58 (52–64)

72 (58–82)

69 (62–75)

 < 0.001

 > 0.05

 < 0.01

Leukocytes (/ml)

6.21 (5.13–7.43)

6.3 (4.68–8.61)

8.77 (6.1–11.53)

 > 0.05

 < 0.01

 < 0.01

Neutrophils (/mm3)

3.38 (2.81–4.22)

4.65 (3.32–7.21)

5.78 (4.31–8.19)

 < 0.001

 < 0.001

 > 0.05

Lymphocytes (/mm3)

2.2 (1.71–2.49)

0.92 (0.65–1.23)

1.97 (0.87–2.2)

 < 0.001

 > 0.05

 < 0.001

CRP (mg/L)

1.0 (0.5–2.4)

60 (27–146)

4.8 (2.1–9)

 < 0.001

 > 0.05

 < 0.001

Fibrinogen (g/L)

2.88 (2.56–3.43)

5.24 (4.03–6.23)

3.43 (3.18–4.15)

 < 0.001

 > 0.05

 < 0.01

KL-6 (U/mL)

254 (191–308)

405 (277–592)

897 (550–1885)

 < 0.001

 < 0.001

 < 0.001

  1. Data are expressed in median (IQR, inter quartile range)
  2. Data are analyzed with Kruskall Wallis test and post Hoc: DunnTest and with Fisher’s test for the sex variable
  3. aHS (healthy subjects): Complete blood count: N = 62; CRP: N = 52; Fibrinogen: N = 46