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Fig. 5 | Respiratory Research

Fig. 5

From: Physiologically variable ventilation reduces regional lung inflammation in a pediatric model of acute respiratory distress syndrome

Fig. 5

Left panels depict pulmonary inflammation characterized by PET imaging normalized to the tissue fraction. Right panels show pulmonary circulation characterized by SPECT imaging, normalized to tissue fraction. Upper panels represent mean PET and SPECT intensities averaged for the entire lung. Middle panels demonstrate the regional distribution based on aeration zones. Bottom panels represent the regional distribution based on the dependent (dorsal) and non-dependent (ventral) zones. SUV: standardized uptake value; PCV: pressure-controlled ventilation; PVV: physiological variable ventilation; ARDS: presence of lung injury; CTRL: absence of lung injury. *p < 0.05 vs. well-aerated or vs. dorsal, †p < 0.05 vs. PCV

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