TY - JOUR AU - Nemoto, Masahiro AU - Nei, Yuichiro AU - Bartholmai, Brian AU - Yoshida, Kazuki AU - Matsui, Hiroki AU - Nakashita, Tamao AU - Motojima, Shinji AU - Aoshima, Masahiro AU - Ryu, Jay H. PY - 2020 DA - 2020/10/20 TI - Automated computed tomography quantification of fibrosis predicts prognosis in combined pulmonary fibrosis and emphysema in a real-world setting: a single-centre, retrospective study JO - Respiratory Research SP - 275 VL - 21 IS - 1 AB - Combined pulmonary fibrosis and emphysema (CPFE) is a heterogeneous clinico-radiological syndrome without a consensus definition. There are limited data on the relation between the amount of parenchymal fibrosis and prognosis. In this study, we assessed the prognostic implications of the extent of fibrosis assessed by an automated quantitative computed tomography (CT) technique and the radiological and functional change over time in patients with a broad spectrum of fibrotic interstitial lung diseases (ILDs) encountered in a real-world setting. SN - 1465-993X UR - https://doi.org/10.1186/s12931-020-01545-3 DO - 10.1186/s12931-020-01545-3 ID - Nemoto2020 ER -