Table 1 Baseline characteristics of patients with IgG4-RLD
From: Long-term clinical course and outcomes of immunoglobulin G4-related lung disease
n = 37 | |
|---|---|
Age, years | 55.6 ± 15.0 |
Male sex | 29 (78.4) |
Smoking status | |
Current smoker | 9 (24.3) |
Ex-smoker | 19 (51.4) |
Never smoker | 9 (24.3) |
Amount of smoking, pack-years | 30.7 ± 33.2 |
Comorbidities | |
Hypertension | 9 (24.3) |
Diabetes | 6 (16.2) |
Stroke | 1 (2.7) |
Underlying lung disease | |
Tuberculosis sequelae | 7 (18.9) |
Chronic obstructive pulmonary disease | 2 (5.4) |
Pneumoconiosis | 1 (2.7) |
Serum IgG total, mg/dL | 1935.7 ± 741.1 |
Serum IgG4, mg/dL | 158.9 ± 129.5 |
Serum albumin globulin ratio | 0.9 ± 0.4 |
Presence of extrapulmonary organ involvement | 16 (45.9) |
Pancreas | 10 (62.5) |
Retroperitoneum | 5 (31.3) |
Biliary tract | 3 (18.8) |
Kidney | 3 (18.8) |
Lacrimal glands | 3 (18.8) |
Othersa | 8 (43.8) |
Pulmonary function test (n = 30) | |
Normal | 11 (36.7) |
Restrictive | 10 (33.3) |
Obstructive | 9 (30.0) |
FVC, %pred | 82.4 ± 17.5 |
FEV1, %pred | 81.4 ± 18.0 |
FEV1/FVC | 0.8 ± 0.1 |
DLCO, %pred | 75.5 ± 20.7 |
TLC, %pred | 85.2 ± 13.67 |
Bronchoalveolar lavage (n = 13)b | |
White blood cell, /µL | 447.7 ± 405.6 |
Neutrophil (%) | 8.3 ± 14.2 |
Lymphocyte (%) | 16.1 ± 13.0 |
Radiologic subtype | |
Alveolar consolidative | 11 (29.7) |
Solid nodular | 11 (29.7) |
Bronchovascular | 8 (21.6) |
Alveolar interstitial | 5 (13.5) |
Round ground glass opacity | 2 (5.4) |