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Table 2 Coefficient and 95% confidence intervals for the effect of diabetes on the pulmonary function

From: Non-linear association between diabetes mellitus and pulmonary function: a population-based study

 

DM with Hba1c < 7

DM with Hba1c > = 7

FEV1

PC

FVC

PC

FEV1

PC

FVC

PC

Model 1 adjusted for

− 6.54 [− 8.17, − 4.91]

 

− 7.21 [− 8.94, − 5.47]

 

− 6.68 [− 8.83, − 4.53]

 

− 9.17 [− 11.47, − 6.87]

 

Additionally adjusted for

        

HbA1c

− 4.17 [− 6.03, − 2.32]

36.3%

− 4.71 [− 6.66, − 2.77]

34.6%

− 4.88 [− 8.35, − 1.41]

31.1%

− 7.20 [− 10.73, − 3.67]

24.7%

FPG

− 4.62 [− 8.16, − 1.10]

32.5%

− 5.89 [− 9.22, − 2.56]

21.2%

− 4.83 [− 9.71, 0.06]

24.2%

− 7.22 [− 12.23, − 2.21]

17.1%

2 h-PG

− 3.19 [− 8.02, 1.65]

40.3%

− 3.55 [− 8.10, 1.01]

43.2%

IO

IO

IO

IO

log (HOMA-IR)

− 5.81 [− 8.77, − 2.85]

15.4%

− 5.33 [− 8.12, − 2.54]

26.9%

− 5.33 [− 8.06, − 2.59]

19.7%

− 6.83 [− 9.47, − 4.19]

23.5%

BMI

− 6.01 [− 7.91, − 4.30]

6.7%

− 6.39 [− 7.97, − 4.81]

11.5%

− 6.12[ − 8.18, − 4.07]

8.6%

− 8.24 [− 10.10, − 6.38]

10.4%

waist circumference

− 5.62 [− 7.41, − 3.83]

15.5%

− 6.06 [− 7.67, − 4.45]

17.6%

− 5.21 [− 7.25, − 3.17]

20.6%

− 7.55 [− 9.42, − 5.67]

17.6%

log (C-reactive protein)

− 4.89 [− 6.70, − 3.08]

12.7%

− 5.97 [− 7.75, − 4.18]

12.0%

− 4.92 [− 7.69, − 2.15]

24.8%

− 8.46 [− 10.85, − 6.06]

11.3%

  1. PC Percentage mediation, IO insufficient observation, FPG fasting plasma glucose, 2 h-PG plasma glucose 2 h after OGTT, HOMA-IR homeostasis model of assessment for insulin resistance index
  2. Model 1 adjusted age, race, sex, education, and METs