Lung function, pharmacokinetics, and tolerability of inhaled indacaterol maleate and acetate in asthma patients

Respiratory Research

Table 3 Comparative analysis of PK between indacaterol maleate and acetate on Day 14

	Indacaterol maleate 150 μg o.d. (N = 51)	Indacaterol acetate 150 μg o.d. (N = 52)	Indacaterol acetate versus Indacaterol maleate
Geometric LSM ratio (90% CI)
AUC_0-24h,ss, h*pg/mL	2180 (2020 to 2350)	1950 (1820 to 2100)	0.897 (0.854 to 0.942)
C_max,ss, pg/mL	253 (236 to 273)	226 (210 to 243)	0.891 (0.846 to 0.939)

AUC Area under the curve, C_max Maximum plasma concentration, LSM Least square mean, o.d. Once daily, PK Pharmacokinetics

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