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Table 3 Odds Ratios and 95% Confidence Interval (CI) for Emphysema Based on Stepwise Multiple Logistic Regression models with Clinical Characters and Biomarkers. (222 subjects)

From: Value of metalloproteinases in predicting COPD in heavy urban smokers

Predictors

OR

95% CI

Age

1.06

(1.01,1.11)

FEV1/FVC

0.92

(0.88,0.96)

Pack-Years

1.02

(1.01,1.04)

log2(MMP-1)

0.75

(0.52,1.06)

log2(MMP-7)

1.40

(0.98,2.02)

  1. AIC = 237.93
  2. Smokers without Emphysema are Baseline
  3. The full models contained Age, Smoking duration (year), Pack-Years, FEV1/FVC, Cough (Yes vs. No), log2(TIMP-1), log2(TIMP-2), log2(MMP-1), log2(MMP-2), log2 (MMP-7), log2(MMP-9)
  4. Final model: Log-odds of emphysema = 1.06*Age+ 1.02*Pack-Years+ 0.92* FEV1/FVC + 0.75 *log2(MMP-1) + 1.40* log2(MMP-7)
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Respiratory Research

ISSN: 1465-993X

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