Table 1 Clinical Characteristics by Emphysema Status in Smokers in Batch 1 and Batch 2 (222 subjects)
From: Value of metalloproteinases in predicting COPD in heavy urban smokers
Smokers without Emphysema | Smokers with Emphysema | P value | |||
|---|---|---|---|---|---|
Mean ± SD or % | N | Mean ± SD or % | N | ||
Age (years)† | 60.8 ± 7.1 | 121 | 64.8 ± 7.0 | 101 | < 0.0001 |
Height (cm)† | 169.1 ± 10.0 | 120 | 170.3 ± 9.2 | 101 | 0.51 |
Weight (kg)† | 80.9 ± 17.8 | 120 | 79.4 ± 18.7 | 101 | 0.50 |
BMI† | 28.2 ± 5.3 | 120 | 27.2 ± 5.3 | 101 | 0.24 |
Start smoke age† | 16.9 ± 4.0 | 121 | 16.6 ± 4.5 | 101 | 0.80 |
Cigarettes Daily† | 24.0 ± 11.0 | 121 | 26.3 ± 11.1 | 101 | 0.11 |
Smoke Duration Years† | 31.7 ± 11.5 | 121 | 39.6 ± 10.8 | 101 | < 0.0001 |
Pack Years† | 37.2 ± 20.4 | 121 | 50.9 ± 23.8 | 101 | < 0.0001 |
FEV1/FVC† | 75.5 ± 7.9 | 111 | 67.5 ± 10.6 | 95 | < 0.0001 |
Gender | 121 | 102 | |||
Female | 61 (50%) | 45 (45%) | 0.42 | ||
Male | 60 (50%) | 57 (55%) | |||
Race | 121 | 102 | 0.06 | ||
African American | 4 (3%) | 9 (9%) | |||
Asian | 0 (0%) | 1 (1%) | |||
Caucasian | 110 (91%) | 90 (89%) | |||
Indian | 1 (1%) | 0 (0%) | |||
Other | 6 (5%) | 1 (1%) | |||
Cough | 121 | 102 | 0.04 | ||
Yes | 20 (17%) | 29 (29%) | |||
No | 101 (83%) | 73 (71%) | |||
Current Smoker | 121 | 102 | 0.01 | ||
Yes | 38 (31%) | 49 (49%) | |||
No | 83 (69%) | 52 (51%) | |||
Phlegm | 120 | 101 | 0.11 | ||
Yes | 8 (7%) | 14 (14%) | |||
No | 112 (93%) | 86 (86%) | |||
MRC Score | 121 | 101 | 0.12 | ||
0 | 87 (72%) | 63 (62%) | |||
1 | 12 (10%) | 23 (23%) | |||
2 | 8 (7%) | 5 (5%) | |||
3 | 2 (2%) | 3 (3%) | |||
4 | 6 (5%) | 5 (5%) | |||
5 | 6 (5%) | 2 (2%) | |||
MMP10 | 121 | 101 | 0.40 | ||
Detectable | 75 (62%) | 69 (68%) | |||
Undetectable | 46 (38%) | 32 (32%) | |||