Oxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model

Table 1 Anthropometric characteristics, spirometry values of the subjects

	Nonsmoker n = 9	Non-COPD Smoker n = 9	COPD smoker n = 9	P value
Gender (M/n)	66.7% (6/9)	77.8% (7/9)	77.8% (7/9)	0.825 ^a
Age (years)	56.22 ± 10.99	57.44 ± 5.72	57.67 ± 6.50	0.92^b
Smoking history (pack-year)	0	40.33 ± 13.61	39.56 ± 14.87	0.23^c
FEV₁/Pre (%)	85.11 ± 3.82	85.56 ± 4.22	71.78 ± 3.96	<0.01^b
FEV₁/FVC (%)	81.33 ± 5.57	81.11 ± 5.82	63.44 ± 3.50	<0.01^b

^a P by Chi-square test, ^bP by one-way ANOVA test, and ^c P by Student’s t test

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