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Fig. 4 | Respiratory Research

Fig. 4

From: Oxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model

Fig. 4

Hypermethylation of the Bcl-2 promoter in COPD patients. Compared to the normal (nonsmokers) group, the COPD group had an elevated Bcl-2 promoter methylation level (%) (1.62 ± 2.31 vs. 8.28 ± 3.29, P < 0.01 by one-way ANOVA and LSD test). There was no significant difference in the Bcl-2 promoter methylation level between the nonsmoker and non-COPD smoker groups (1.62 ± 2.31 vs. 2.02 ± 2.48, P = 0.756 by one-way ANOVA and LSD test). *P < 0.05 vs. Nonsmoker group. The data in the figure represent the mean ± SD

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Respiratory Research

ISSN: 1465-993X

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