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Table 3 Infant outcomes in first-time pregnancies (excluding stillbirths) with a history of at least two sarcoidosis-coded health care visits (n = 181) and general population comparator pregnancies (n = 6604) in Sweden, crude and adjusted risk ratios, 2002–2013

From: Maternal and infant outcomes in sarcoidosis pregnancy: a Swedish population-based cohort study of first births

  Sarcoidosis
pregnancies
n (%)
General population
pregnancies
n (%)
Crude
Risk Ratio
(95% CI)
Adjusted
Risk Ratioa
(95% CI)
Preterm (< 37 wks gestation) 20 (11.1) 416 (6.3) 1.8 (1.1, 2.7) 1.7 (1.1, 2.5)
Very preterm (< 32 wks gestation) < 5 52 (0.8) NA NA
Small Size for gestational age < 5 188 (3.0) NA NA
Large Size for gestational age < 5 102 (1.6) NA NA
Apgar at 5 min < 7 < 5 88 (1.3) NA NA
Major birth defectb 11 (6.1) 245 (3.7) 1.6 (0.9, 2.9) 1.6 (0.9, 2.8)
Infection (within 3 mo)b 10 (5.5) 369 (5.6) 1.0 (0.5, 1.8) 0.9 (0.5, 1.7)
Neonatal death 0 (0) 8 (0.1) NA NA
  1. NA Not assessed if less than 5 cases to minimize identifiability of individuals
  2. aAdjusted for maternal age, calendar year and educational level. The models for preterm birth and major birth defects were additionally adjusted for body mass index and smoking status
  3. bInfants with a missing ID number were excluded due to inability to link to the patient register (n = 4, all excluded were general population comparator pregnancies)