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Table 2 Laboratory and radiographic findings of COVID-19 patients on admission

From: Risk factors for the critical illness in SARS-CoV-2 infection: a multicenter retrospective cohort study

 

Reference values

Total (n = 252)

Non-critically ill (n = 200)

Critically ill (n = 52)

p value

Laboratory findings

 White blood cell count (X 109/L)

3.50–9.50

5.05 (4.02–6.83)

4.85 (3.88–6.30)

6.45 (4.53–10.91)

< 0.0001

 Lymphocyte count (X 109/L)

1.10–3.20

1.03 (0.72–1.41)

1.12 (0.74–1.51)

0.79 (0.58–1.07)

0.0003

 Neutrophil count (X 109/L)

1.80–6.30

3.28 (2.36–4.75)

3.05 (2.31–4.19)

4.87 (2.86–8.37)

< 0.0001

 Monocyte count (X 109/L)

0.10–0.60

0.36 (0.23–0.54)

0.36 (0.22–0.55)

0.36 (0.24–0.54)

0.654

 Platelet count (X 109/L)

125.00–350.00

176.50 (141.00–217.00)

174.50 (140.75–205.25)

194.00 (148.00–274.50)

0.063

 NLR

0.78–3.53

3.10 (2.01–5.62)

2.74 (1.92–4.33)

6.51 (2.54–14.12)

< 0.0001

 APTT (s)

21.00–37.00

30.20 (25.56–35.50)

29.04 (25.41–34.43)

34.20 (28.61–36.39)

0.003

 FIB (g/L)

2.00–4.00

3.32 (2.68–4.10)

3.20 (2.60–3.88)

3.70 (3.11–4.86)

0.0005

 D-dimer (μg/mL)

0.00–0.55

0.40 (0.28–0.61)

0.37 (0.25–0.55)

0.50 (0.31–1.30)

0.007

 ESR (mm/1 h)

0.00–30.00

24.00 (12.00–40.00)

20.00 (9.50–38.00)

31.00 (23.75–45.25)

0.002

 PCT (ng/mL)

0.00–0.50

0.11 (0.06–0.26)

0.10 (0.05–0.25)

0.24 (0.10–0.37)

< 0.0001

 CRP (mg/L)

0.00–10.00

15.75 (5.15–43.82)

13.02(4.75–36.39)

24.70 (6.89–100.19)

0.001

 LDH (U/L)

91.00–230.00

193.40 (156.75–239.15)

188.00 (151.00–236.00)

226.00 (183.00–323.10)

0.001

 CK (U/L)

25.00–200.00

99.00 (68.45–175.00)

95.00 (70.00–170.50)

150.00 (47.85–186.50)

0.68

 Creatinine (μmol/L)

44.00–112.00

71.90 (59.00–85.93)

71.40 (59.00–85.47)

74.19 (62.05–86.00)

0.829

 BUN (mmol/L)

2.50–7.10

4.35 (3.40–5.66)

3.92 (3.25–5.37)

5.41 (4.16–6.90)

< 0.0001

 AST (U/L)

0.00–40.00

31.00 (24.10–43.75)

31.00 (24.00–41.00)

37.00 (25.70–56.00)

0.018

 ALT (U/L)

0.00–50.00

31.00 (17.00–45.40)

29.00 (15.00–42.50)

36.45 (22.48–56.03)

0.01

 TBIL (μmol/L)

3.00–21.00

10.40 (7.60–16.85)

9.80 (7.30–13.80)

17.20 (8.65–23.53)

< 0.0001

 SOFA score

 

1.00 (0.00–3.00)

1.00 (0.00–1.25)

4.00 (3.00–5.00)

< 0.0001

Imaging features

 Ground-glass opacity

 

62 (24.60)

50 (25.00)

12 (23.10)

0.774

 Unilateral pulmonary abnormality

 

45 (17.90)

40 (20.00)

5 (9.60)

0.082

 Bilateral pulmonary abnormality

 

179 (71.00)

145 (72.50)

34 (65.40)

0.314

  1. Data are median (IQR) or n (%). p values are from Mann-Whitney U test, χ2 test, or Fisher’s exact test, as appropriate. NLR Neutrophil-to-lymphocyte ratio, APTT Activated partial thromboplastin time, FIB Fibrinogen, ESR Erythrocyte sedimentation rate, PCT Procalcitonin, CRP C-reactive protein, LDH Lactate dehydrogenase, CK Creatine kinase, BUN Blood urea nitrogen, AST Aspartate transaminase, ALT Alanine aminotransferase, TBIL Total bilirubin, SOFA Sequential Organ Failure Assessment