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Table 4 Risk factors for recurrence of lung cancer

From: Presence of heat shock protein 47-positive fibroblasts in cancer stroma is associated with increased risk of postoperative recurrence in patients with lung cancer

Characteristics

Univariate analysis

Multivariate analysis

OR

(95% CI)

P value

OR

(95% CI)

P value

Age

1.015

(0.9717–1.063)

p = 0.498

   

Sex Male

6.109

(1.987–26.75)

p < 0.001*

3.071

(0.611–18.84)

p = 0.176

BMI (kg/m2)

1.082

(0.919–1.304)

p = 0.351

   

History of smoking

4.665

(1.642–16.82)

p = 0.003*

1.478

(0.321–7.852)

p = 0.622

Pulmonary function test

 %VC

0.986

(0.960–1.000)

p = 0.121

   

 FEV1/FVC

0.958

(0.934–1.019)

p = 0.264

   

 %DLCO

0.991

(0.971–1.000)

p = 0.244

   

KL-6

1.002

(0.999–1.006)

p = 0.175

   

Adenocarcinoma

0.362

(0.149–0.886)

p = 0.027*

0.733

(0.263–2.037)

p = 0.550

HSP47 expression in lung cancer (Positive)

0.586

(0.230–1.586)

p = 0.283

   

Number of HSP47-positive fibroblasts (High)

8.437

(2.351–54.07)

p = 0.004*

4.371

(1.054–29.83)

p = 0.042*

  1. *; P value < 0.05, Logistic regression analysis
  2. OR odds ratio, CI confidence interval, BMI body mass index, DLCO diffusing capacity for carbon monoxide
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Respiratory Research

ISSN: 1465-993X

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