TY - JOUR AU - Miyamura, Takuto AU - Sakamoto, Noriho AU - Ishida, Kaori AU - Kakugawa, Tomoyuki AU - Taniguchi, Hirokazu AU - Akiyama, Yoshiko AU - Okuno, Daisuke AU - Hara, Atsuko AU - Kido, Takashi AU - Ishimoto, Hiroshi AU - Miyazaki, Takuro AU - Matsumoto, Keitaro AU - Tsuchiya, Tomoshi AU - Yamaguchi, Hiroyuki AU - Miyazaki, Taiga AU - Obase, Yasushi AU - Ishimatsu, Yuji AU - Nagayasu, Takeshi AU - Mukae, Hiroshi PY - 2020 DA - 2020/09/14 TI - Presence of heat shock protein 47-positive fibroblasts in cancer stroma is associated with increased risk of postoperative recurrence in patients with lung cancer JO - Respiratory Research SP - 234 VL - 21 IS - 1 AB - Heat shock protein 47 (HSP47), a collagen-binding protein, has a specific role in the intracellular processing of procollagen production. HSP47 expression is associated with cancer growth and metastasis in several types of cancers. However, none of the studies have assessed whether HSP47 expression is associated with the risk of postoperative recurrence of lung cancer until now. Therefore, we aimed to assess this association. SN - 1465-993X UR - https://doi.org/10.1186/s12931-020-01490-1 DO - 10.1186/s12931-020-01490-1 ID - Miyamura2020 ER -