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Fig. 2 | Respiratory Research

Fig. 2

From: Azithromycin ameliorates sulfur dioxide-induced airway epithelial damage and inflammatory responses

Fig. 2

SO2 exposure results in increased expression of members of the Glutathione S Transferase family. a. Glutathione S transferase is increased in BALF in SO2 exposed mice. BALF samples were analysed by mass spectrometry. Of the samples showing dramatic changes from controls, 6 GST analogs were detected and demonstrated to be increased in BALF samples of SO2 exposed mice. Data represent a single measurement from a pooled sample from six mice in each treatment group. b. The increased GST concentration in BALF seen in SO2 exposed mice is attenuated by pre-treatment with AZM. The six GSTs shown previously all had reduced BALF concentrations when mice were pre-treated with AZM. Data represent a single measurement from a pooled sample from six mice in each treatment group

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