Table 1 Characteristics of the patients included in the study and having TBLCs performed for the diagnosis of a DPLD
Overall population (n = 81) | Specific histological pattern (n = 52) | NSIP or nondiagnostic pattern (n = 29) | p value | ||
|---|---|---|---|---|---|
Gender | Male N (%) | 40 (49) | 28 (54) | 12 (41) | NS |
Age, years | Median (range) | 62 (26–81) | 62 (26–81) | 64 (32–75) | NS |
Smoking history | Current N (%) | 11 (14) | 7 (13) | 4 (14) | NS |
Former N (%) | 43 (53) | 28 (54) | 15 (52) | NS | |
Never N (%) | 27 (33) | 17 (33) | 10 (34) | NS | |
BMI | Median (range) | 28 (17–39) | 27 (17–39) | 29 (18–39) | NS |
FVC, % predicted value | Median (range) | 78 (40–134) | 78 (40–130) | 79 (41–134) | NS |
DLCO, % predicted value | Median (range) | 52 (20–85) | 52 (20–79) | 48 (28–85) | NS |
HRCT | Typical UIP N (%) | 1 (1) | 1 (2) | 0 (0) | NS |
Probable UIP N (%) | 9 (11) | 5 (10) | 4 (14) | NS | |
Indeterminate for UIP N (%) | 30 (37) | 19 (37) | 11 (38) | NS | |
Alternative diagnostic N (%) | 41 (51) | 27 (52) | 14 (48) | NS | |
Number of biopsies/patient | Mean (range) | 4 (1–5) | 4 (2–5) | 4 (1–5) | NS |
Size of biopsies (mm2) | By specimen Mean (range) | 20,9 (9–44) | 22 (10–44) | 18 (9–40) | 0.049 |
By patient Mean (range) | 76,5 (30–152) | 82 (39–152) | 65 (30–120) | 0.007 |