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Table 3 Sensitivity and specificity of the ten main variables to identify cluster B, utilizing the cut-off values giving the best sum of sensitivity and specificity (The Youden index)

From: Cluster analysis in 975 patients with current cough identifies a phenotype with several cough triggers, many background disorders, and low quality of life

Variable

Cut-off value

Sensitivity

Specificity

Trigger sum

≥ 5

85%

80%

Number of cough background disorders

≥ 1

88%

74%

Absence of idiopathic cough

Yes/no

88%

74%

LCQ physical domain

≤ 4.7

81%

71%

LCQ question 9 a

≤ 5

73%

77%

LCQ total score

≤ 15.0

76%

76%

Dyspnea with wheezing

Yes/no

65%

85%

Strong paints or fumes as a cough trigger

Yes/no

68%

81%

Current asthma

Yes/no

56%

96%

Current medication for asthma

Yes/no

58%

88%

  1. a Leicester Cough Questionnaire question number 9: “In the last 2 weeks, exposure to paints or fumes has made me cough” with a 7-step scale from 1 = all of the time to 7 = none of the time