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Table 3 Rate ratio of annual exacerbations according to ICS use by baseline eosinophil count (cells/μL)

From: Blood eosinophils as a biomarker of future COPD exacerbation risk: pooled data from 11 clinical trials

  

≤ 150 cells/μL

> 150–≤ 300 cells/μL

> 300 cells/μL

Baseline ICS use

No n = 8830

Rate: 0.45

Rate: 0.48

RR: 1.07

(95% CI 0.97, 1.17)

Rate: 0.49

RR: 1.09

(95% CI 0.98, 1.21)

Yes n = 13,295

Rate: 0.75

Rate: 0.79

RR: 1.05

(95% CI 0.99, 1.11)

Rate: 0.82

RR: 1.09

(95% CI 1.02, 1.17)

  1. RR versus ≤ 150 cells/μL eosinophil subgroup.
  2. CI Confidence interval; ICS Inhaled corticosteroids; RR Rate ratio.