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Table 1 Baseline characteristics of the population

From: Sonic hedgehog signalling as a potential endobronchial biomarker in COPD

 

Non-COPD (n = 30)

COPD (n = 28)

p-value

Sex ratio H/F

13/17

17/11

ns

Age (years)

53.9 ± 15.3

62.1 ± 10.6

ns

Smoking history

  

0.009

 Never smokers

8 (27%)

0

 

 Current-smokers

12 (40%)

12 (43%)

 

 Former-smokers

10 (33%)

16 (57%)

 

 Pack-years

21 ± 21

41 ± 22

< 0.001

Spirometry

 FEV1, % of predicted value

97 ± 19

55 ± 25

< 0.0001

 FVC, % of predicted value

100 ± 18

82 ± 20

0.003

 FEV1/FVC %

81 ± 9

49 ± 12

< 0.0001

Spirometric GOLD 1/2/3/4

NA

7/6/9/6

GOLD ABCD (mMRC)

NA

8/6/6/8

GOLD ABCD (CAT)

NA

7/7/4/10

Frequent exacerbation (> 1/year)

10 (36%)

  1. Data are expressed as mean ± SD or number (%) FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, mMRC modified medical research council, CAT COPD assessment test
  2. ns: non-significate