From: A comparison of four different models of acute respiratory distress syndrome in sheep
Lavage | Albumin 20% | HCl | LPS | p < 0.05 | |
---|---|---|---|---|---|
N | 6 | 10 | 6 | 5 | |
Death during exp | 0 | 0 | 0 | 1 | |
Cells BALF (corr) (cells/kg) | 43.7 ± 19.4 | 204.7 ± 509.2 | 38 ± 33.5 | 73.2 ± 53.5 | no |
Neutro BALF (corr) (cells/kg) | 12.5 ± 8.8 | 58.4 ± 142.2 | 29.3 ± 30.1 | 8.2 ± 7.1 | no |
Protein BALF (corr) (mg/kg) | 60.1 ± 41.6 | 89.5 ± 80.4 | 54.4 ± 40.8 | 32.3 ± 22.2 | no |
DSPL BALF (corr) (mg/kg) | 0.087 ± 0.061 | 0.103 ± 0.061 | 0.071 ± 0.011 | 0. 132 ± 0.09 | no |
IL-8 BALF (corr) (ng/kg) | 6.66 ± 5.67 | 4.42 ± 5.5 | 3.46 ± 1.82 | 6.95 ± 2.5 | no |
MAS (μm2) | 6782 ± 1665 | 7078 ± 1694 | 7634 ± 3705 | 5158 ± 2400 | no |
AWT (μm2) | 26.2 ± 2.1 | 27.8 ± 2.2 | 30 ± 3.8 | 29.4 ± 2.7 | no |
Lung injury score | 0.025 ± 0.004 | 0.023 ± 0.003 | 0.024 ± 0.004 | 0.025 ± 0.003 | no |