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Table 1 Patient Demographics and Baseline Characteristics in Studies A and B (Safety Population)

From: Navafenterol (AZD8871) in healthy volunteers: safety, tolerability and pharmacokinetics of multiple ascending doses of this novel inhaled, long-acting, dual-pharmacology bronchodilator, in two phase I, randomised, single-blind, placebo-controlled studies

 

Study A

Study B

Placebo

n = 6

Navafenterol

300 μg

n = 6

Navafenterol

600 μg

n = 6

Navafenterol

900 μg

n = 6

Placebo

n = 6

Navafenterol

300 μg

n = 6

Navafenterol

600 μg

n = 6

Navafenterol

900 μg

n = 6

Age, years

41.5 (7.6)

34.0 (5.7)

44.2 (7.9)

36.5 (6.8)

35.7 (6.4)

30.0 (5.0)

32.0 (7.8)

35.5 (8.5)

Race, n (%)

 Asian

0

1 (16.7)

0

0

6 (100.0)

6 (100.0)

6 (100.0)

6 (100.0)

 Black/African American

0

0

0

1 (16.7)

0

0

0

0

 White

6 (100.0)

5 (83.3)

6 (100.0)

5 (83.3)

0

0

0

0

Ethnicity, n (%)

 Hispanic or Latino

1 (16.7)

0

1 (16.7)

0

0

0

0

0

Height, cm

179.7 (4.7)

179.7 (6.3)

174.2 (8.0)

176.8 (3.3)

168.5 (4.7)

172.0 (2.6)

172.8 (5.6)

170.8 (6.3)

Weight, kg

78.0 (11.1)

85.2 (13.2)

75.8 (5.25)

76.2 (8.4)

64.3 (5.1)

62.8 (5.3)

68.0 (9.3)

64.8 (6.2)

Body mass index, kg/m2

24.1 (2.6)

26.2 (2.3)

24.8 (3.7)

24.3 (1.8)

22.7 (2.0)

21.2 (1.3)

22.7 (2.1)

22.2 (2.4)

  1. Data are mean (standard deviation) unless otherwise specified