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Fig. 1 | Respiratory Research

Fig. 1

From: Pregnancy-associated plasma protein A – a new indicator of pulmonary vascular remodeling in chronic thromboembolic pulmonary hypertension?

Fig. 1

Impact of treatment on pregnancy-associated plasma protein A (PAPP-A) levels in patients with chronic thromboembolic pulmonary hypertension (CTEPH). The left panel shows PAPPA-A levels in CTEPH patients before undergoing treatment with pulmonary endarterectomy (PEA BL) or balloon pulmonary angioplasty (BPA BL) and 12 months after PEA (PEA 12-MFU) respectively 6 months after the final BPA (BPA 6-MFU) procedure compared to controls of patients with pulmonary hypertension in whom CTEPH was excluded (PH Controls). The right panel shows the time dependent effect of the staged BPA procedure on PAPP-A levels. For comparison, data on NT-proBNP as a biomarker reflecting hemodynamics is provided. * Indicates p-value < 0.05 comparing difference in PAPP-A level at procedure compared to the baseline level

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