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Table 3 Correlation analysis of lipid mediator levels and clinical parameters in ABPA

From: Analysis of serum polyunsaturated fatty acid metabolites in allergic bronchopulmonary aspergillosis

Rho

AA

15(S)- HPETE

12(S)- HPETE

5(S)- HPETE

15(S)- HETE

12(S)- HETE

11(S)- HETE

8(S)- HETE

5(S)- HETE

LTB4

15(S)- HEPE

12(S)- HEPE

5(S)- HEPE

13(S)- HPODE

9(S)- HPODE

12 HHTrE

PGD2

PGB2

tIgE (kU/l)

0.63*

0.15

0.33

0.37

0.14

0.33

0.41

0.26

− 0.08

− 0.51

− 0.31

0.11

− 0.29

0.29

0.24

0.32

− 0.15

− 0.20

Af. sIgE (kU/l)

0.25

0.36

0.58*

0.29

0.23

0.40

0.33

0.32

0.06

0.11

0.59*

0.73**

0.44

0.20

0.24

0.05

0.42

−0.03

NEU in Blood(109/L)

0.36

0.22

0.45

0.18

0.06

0.15

0.53

0.30

−0.03

− 0.38

− 0.21

0.04

− 0.17

0.26

0.27

0.43

0.08

0.13

NEU in Blood (%)

−0.23

0.26

0.68*

0.30

0.22

0.10

−0.01

0.13

0.01

0.15

0.58*

0.24

0.30

0.06

0.10

−0.27

0.37

−0.05

EOS in Blood (109/L)

0.41

−0.25

−0.13

− 0.63*

0.71*

0.69*

0.55

0.31

0.66*

0.43

0.07

−0.14

0.38

−0.39

−0.42

0.62*

0.28

−0.13

EOS in Blood (%)

0.41

−0.30

−0.17

− 0.59*

0.78**

0.74**

0.56

0.28

0.56

0.45

0.16

−0.04

0.38

−0.46

−0.49

0.61*

0.24

−0.09

NEU in Sputum (%)

0.41

0.32

0.22

−0.20

0.64*

0.32

0.43

0.46

0.55

0.65*

0.45

0.19

0.77**

0.13

0.14

0.30

0.24

0.01

EOS in Sputum (%)

−0.42

−0.65*

−0.86**

−0.45

0.03

0.20

−0.11

−0.19

0.00

0.10

−0.14

−0.22

− 0.23

−0.68*

− 0.70

0.08

− 0.12

0.38

LYM in Sputum (%)

0.00

−0.48

−0.44

− 0.24

−0.17

− 0.23

0.14

− 0.06

−0.23

− 0.32

−0.68*

− 0.49

−0.64*

− 0.28

−0.30

0.38

−0.73**

0.30

%FEV1

0.58*

0.35

0.19

−0.17

0.37

0.32

0.80**

0.40

0.16

−0.06

0.23

0.26

0.41

0.22

0.25

0.70*

0.22

0.20

FEV1/FVC (%)

0.23

−0.36

−0.20

−0.32

0.09

0.24

−0.02

−0.65

− 0.28

−0.24

− 0.18

−0.23

− 0.21

−0.34

− 0.36

0.19

0.35

−0.54

%FEF25–75

0.67*

−0.06

0.19

−0.16

0.66*

0.62*

0.63*

0.15

0.05

0.12

0.30

0.35

0.29

−0.15

−0.17

0.58*

0.18

−0.20

  1. Correlation analyses were performed using Spearman rank test. *P < 0.05, **P < 0.01
  2. TIgE Total IgE, Af.Aspergillus fumigatus, NEU Neutrophils, EOS Eosinophils, LYM Lymphocytes, FVC Forced vital capacity, FEV1 Forced expiratory volume in one second, FEF25–75% Forced expiratory flow from 25 to 75% of FVC, AA Arachidonic acid, HPETE Hydroperoxyeicosatetraenoic acid, HETE Hydroxyeicosatetraenoic acid, LTB4 Leukotriene B4, HEPE Hydroxyeicosapentaenoic acid, HPODE Hydroperoxyoctadecadienoic acid, PGB2 Prostaglandin B2, HHTrE Hydroxyheptadecatrienoic acid
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Respiratory Research

ISSN: 1465-993X

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